Should I be calling here?

I had only been at the table like 4 hands. No reads
but the players had nice sized stacks...
Is my hand even any good at the river?
I was sitting there thinking I'd have been
all in on the turn if I were not so chicken-sh*t
and folded preflop....

PokerStars No-Limit Hold'em, $2 BB (8 handed) FTR converter on zerodivide.cx

UTG ($552.30)
CO ($521.05)
Button ($194)
Hero ($193)

Preflop: Hero is BB with 6:heart:, 5:diamond:.
UTG raises to $8.

Flop: ($27) 6:club:, 2:diamond:, 5:spade: (3 players)
UTG bets $8, CO calls $8, Button calls $8.

Turn: ($51) Q:club: (3 players)
UTG checks, CO bets $20, UTG folds, CO calls $50.

River: ($191) 4:diamond: (2 players)
CO bets $40, Button calls $40.

Final Pot: $271

Nope.

if it was suited i might take a look with that many callers. but unsuited nah

Afterwards though, I looked at the stack sizes of the
specific guys involved.

Do implied odds come in to play here, when I have
relatively little to lose, but tonnes to gain?

Implied odds and pot odds can really only work well if you have a bit of a read on your opponents. One of the main problems is even if you "hit" this hand, you could be in very big trouble. Reverse implied odds say this hand is more trouble than it's worth unless your opponents are morons.

Now I've been on tables where people are aggressive and can't lay down their overpair to a 200xBB bet. Then it's worthwhile.

well on the flop you are most likely good, same goes for the turn

i like the pf fold just because your position is horrible
if you were the button in this example then i of course would advocate a call here

Can't argue too much about the pf call. That being said, it has been my experience that these connecting hands (suited or not) make me the most $$ by far. I almost always call a small raise with this hand (even 54) and take a flop.

You do have to be prepared to let it go post flop obviously if you dont flop well enough to it.

Brunson's original Super System talks in depth about these hands and how you can break a big pair with them.