Party Poker No-Limit Hold'em, $1 BB (10 handed) Party Poker Converter Tool from FlopTurnRiver.com (Format: FCP)

Button ($32.28)
SB ($112.71)
Hero ($126.73)
UTG ($110.10)
UTG+1 ($38.50)
UTG+2 ($124.49)
MP1 ($110.85)
MP2 ($38.35)
MP3 ($109.58)
CO ($15.05)

Preflop: Hero is BB with A , K .
3 folds, MP1 raises to $5, 5 folds, Hero raises to $17, MP1 raises to $41. Hero?

Opp is a multi-tabler playing 20/11 and I have been playing tight aggressive. I post this because it is a fairly common situation with AK, facing a 4-bet from a slightly loose-aggressive opponent, getting good odds. The fact that it is Partypoker and 0.50/1 must also come into consideration. What to do?

I fold. Up it to 18pfr from 11 and I'll probably felt it.

With position I'd flat call and take a flop. AK suited is hard to get away from against a LAG with position for me. I'd put him on a mid pair 99-JJ with the looks of his action.

We're in the BB, out of position.

I puke and put all of the money in.

One of the rare times I fold this. Villian is not a lag, you are not a lag either and oop. You could take a flop I suppose but with Villian having a pfr of 11 and eagerly looking to get it all in on the flop, the worst this guy will have is QQ. Racing one hand, behind the other two.

Flat call the raise and take the flop. It's just AK.
If he's got TT-QQ, you'll flop your card or a flush draw and take it down.
If that doesn't happen, you've pretty much lost the race or villain is holding your outs (ie: AA KK) and you can confidently fold.