You never realized that House = Holmes and Wilson = Watson? Or that House's diagnostic approach was Sherlock Holmes' inductive reasoning? Playing of instruments? How about Living in Apartment 221B?He will go down as one of the best written and acted characters in TV history - even if some of the storyline writing got so terrible in later seasons.
Read an article where Hugh said they don't want to change the makeup of House. He came in a prick and will leave a prick. No getting a puppy or getting soft. He'll remain tortured. The article also made a comparison I never saw because I didn't read it but he was essentially a medical Sherlock Holmes. Wilson was his Holmes. Vicodin instead of cocaine. Medical mysteries. I found it simple yet apt. I for one wil miss the show. He was the most frustrating main character ever. You loved his acerbic wit and personality and Dickish ways but also wanted him to just once, do something nice or express his feelings. He couldn't.